Genetics, prediabetes, and type 2 diabetes

Studies have shown that some people are at a higher risk for prediabetes, type 2 diabetes (T2D), and related complications because of their genes. The problem with these studies is that most of them are based on participants from primarily European backgrounds. Because there is very little racial diversity in these studies, the results don’t translate as well for people from non-European backgrounds, including people who descended from Africa, Asia, or Hispanic countries. Using data from the Kaiser Permanente Research Bank, which has a diverse group of participants, scientists will explore the genes that predict prediabetes and T2D. They’ll also study how these genes relate to disease complications and responses to treatment. The scientists’ long-term goal will be to better understand the genetics of prediabetes and T2D. With this information, doctors will be able to design better ways to accurately identify, prevent, and treat prediabetes and T2D in all people.