The KP Research Bank is a national KP program built to enable world-class research that contributes to advances in health care
KP Research Bank offers a lot of advantages to researchers seeking to examine some of the most difficult challenges in medical science. The robust data and specimen collection from diverse members of a real-world health system, including genomic data resources, offers enormous opportunities for discovery-based research. The retrospective, longitudinal medical records available extend more than 20 years for the majority of the cohort. Working with KPRB data also provides opportunities to work with world-class researchers in KP’s research divisions across the country who have experience working with KP’s medical records data, as well as clinician-scientists with expertise in a broad range of medical conditions. The collaborative research and clinical environment at KP is ideal for translational research and implementation science as projects move from discovery towards clinical application.
KP Research Bank Advantages
Scale
The KP Research Bank is a repository of KP medical records data, survey data, and genetic data collected from more than 400,000 KP members who have voluntarily consented to participate in the KP Research Bank. It includes a general cohort, a pregnancy cohort, and a cancer cohort.
Depth and Scope
The unique combination of genetic data and longitudinal medical records data on a large collection of diverse KP members enables research into the genetic factors that influence disease risk, therapeutic response, and long-term outcomes, including those that are population-specific and that may contribute to health disparities in under-represented populations.
Comprehensive
Medical Records
Because KP is an integrated health system, medical records data covers virtually all primary and secondary care for as long as the member has been with KP, and these records are updated in KP Research Bank’s virtual data warehouse every six months.
Genetic Data
The genetic data includes genotyping on over 395,000 participants using a microarray that includes a common SNP backbone for GWAS and imputation, as well as dense coverage of pathogenic coding variants for a wide range of diseases that have potential value for precision medicine.
Using our Resource
Access to KP Research Bank resources by non-KP researchers requires collaboration with a KP researcher, who can help refine the phenotype of interest. The KP Research Bank hosts data and analytic tools in a secure analytic platform that is managed by KP. Researchers will be given access to this platform to perform analyses.
Use of KP Research Bank resources is intended to facilitate publishable, public domain research that will advance the understanding of health and disease and improve care delivery.
